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SCIENTIFIC PROGRAM
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CONTENTS
PL1. Hematopoiesis
PL2. New Therapeutic Modalities in the Field of Hematology
SS1. Stem Cell Biology
SS2. Standardization of Graft Engineering
SS3. Recent Advances in Hematopoietic Stem Cell Transplantation
SS4. Non-myeloablative Stem Cell Transplantation
SS5. Post-transplant Immunobiology
SS6. New Insight in Acquired Cytopenias
SS7. Stem Cell Transplantation in Autoimmune Disease
SS8. Recent Advances for Management of Hematologic Malignancies
SS9. Molecular Pathogenesis of Hematologic Malignancies
SS10. Gene Therapy and Manipulation of Hematopoietic Stem Cell
SS11. Immune and Cell Therapy for Hematological Disorders
SS12. Hematological Disorders in the Developing Countries
SS13. Infections in Hematologic Malignancies
SS14. Asian Cooperation in the Field of Hematology
SS16. Lymphoma
SS17. Multiple Myeloma
SS18. Update on Hemostasis and Thrombosis
SS19. Some Modifications in the Stem Cell Transplantation(SCT) Procedures Render Them Affordable for Developing Countries
PS. Current Status and Future Direction of International Registries
GL. Special Guest Lecture
PL1. Hematopoiesis
PL1-1. Stem Cells in Chronic Myeloid Leukemia
Eaves Connie, Jiang Xiaoyan, Eaves Allen (Canada)
PL1-2. Unexpected Potential of Adult Stem Cells
Verfaille Catherine (USA)
PL1-3. Stem Cell Repair in Ischemic Heart Disease: An Experimental Model
Orlic Donald (USA)
Contents
PL2. New Therapeutic Modalities in the Field of Hematology
PL2-1. Gene Transfer for Hemophilia and Viral Infection
Kay Mark A. (USA)
PL2-2. Insight into Hematopoiesis from Primate and Human Gene Transfer Studies
Schmidt Manfred (Germany), Hacein-Bey Salima (France), Carbonaro Denise (USA), Wissler Manuela (Germany), LeDeist Francoise (France), Cavazzana-Calvo Marina (France), Kohn Donald B. (USA), Dunbar Cynthia (USA), Fischer Alain (France), Kalle Christof von (Germany)
PL2-3. Treatment Modalities in Hematology: Imatinib Mesylate as Therapy for Chronic Myeloid Leukemia
Gratwohl A. (Switzerland)
Contents
SS1. Stem Cell Biology
SS1-1. Multipotential Hematopoietic Stem Cells in the Bone Marrow
Ogawa Makio (USA)
SS1-2. Role of STAT3 for Hematopoietic Stem Cells
Chung Yang-Jo (Korea), Kim Tae-Min (Korea), Eaves Connie (Canada), Oh Il-Hoan (Korea)
SS1-3. Development, Expansion and Maturation of Hematopoietic Stem Cells in Mouse Embryo
Miyajima Atsushi, Minehata Ken-ichi, Takeuchi Masaki (Japan)
Contents
SS2. Standardization of Graft Engineering
SS2-1. Stem Cell Engineering: The New Generation of Cellular Therapeutics
Pei Xuetao (China)
SS2-2. Allogeneic Peripheral Blood Stem Cell Versus Bone Marrow Transplantations: CD34+ Cell Mobilisation, Graft Composition, Immune Reconstitution and Clinical Outcome
Mauricette Michallet (France)
SS2-3. The Use of Graft Engineering in Allogeneic Transplantation for Myeloid Malignancies
Hertenstein Bernd (Germany)
SS2-4. Regulators of Human Stem Cell Proliferation and Engraftment
Eaves Allen, Cashman Jody, Eaves Connie (Canada)
Contents
SS3. Recent Advances in Hematopoietic Stem Cell Transplantation
SS3-1. New Strategies for BMT and Organ Transplantation
Ikehara Susumu (Japan)
SS3-2. Haploidentical Stem Cell Transplantation for Acute Leukemia
Aversa F. (Italy), Terenzi A. (Italy), Felicini R. (Italy), Carotti A. (Italy), Falcinelli F. (Italy), Tabilio A. (Italy), Velardi A. (Italy), Martelli M.F. (Italy)
SS3-3. Bone Marrow Transplantation for Non-Malignant Disease
Sullivan Keith M (USA)
Contents
SS4. Non-myeloablative Stem Cell Transplantation
SS4-1. Maternal-Fetal Relationship, Natural Chimerism and Bilateral Transplantation Tolerance as the Basis for Non-Myeloablative Stem Cell Transplantation
Slavin Shimon (Israel)
SS4-2. Update on Non-myeloablative Stem Cell Transplantation for Hematologic Malignancies
Giralt S. (USA)
SS4-3. Related and Unrelated Nonmyeloablative Hematopoietic Stem Cell Transplantation for Malignant Diseases
Georges George E. (USA), Maris Michael (USA), Sandmaier Brenda M. (USA), Maloney David G. (USA), LyleFeinstein (USA), Niederweiser Dietger (Germany), Shizuru Judith A. (USA), McSweeney Peter A. (USA), Chauncey Thomas R. (USA), Agura Edward (USA), Little Marie-Trse (USA), Sahebi Firoozeh (USA), Hegenbart Ute (Germany), Pulsipher Michael A. (USA), Bruno Benedetto (Italy), Forman Stephen (USA), Woolfrey Ann (USA), Radich Jerald P. (USA), Blume Karl G. (USA), Storb Rainer (USA)
Contents
SS5. Post-transplant Immunobiology
SS5-1. Immunological Reconstitution and Immunoregulatory Cells in Hematopoietic Stem Cell Transplantation
Imamura Masahiro (Japan)
SS5-2. Cellular and Cytokine Effectors of Acute Graft Versus Host Disease
Ferrara James L.M. (USA)
SS5-3. Post-transplant Immune Recovery and the Implication for Infection Risk
Trigg Michael E. (USA)
Contents
SS6. New Insight in Acquired Cytopenias
SS6-1. Immune Pathophysiology of Aplastic Anemia
Maciejewski Jaroslaw P. (USA), Risitano Antonio (USA), Kook Hoon (USA), Zeng Weihua (USA), Chen Guibin (USA), Young Neal S. (USA)
SS6-2. New Insignts in the Understanding of Myelo-Dysplastic Syndrome (MDS)
Gordon-Smith E.C. (UK)
SS6-3. Haemopoietic Stem Cell Transplantation for Acquired Cytopenias
Hows Jill (UK)
Contents
SS7. Stem Cell Transplantation in Autoimmune Disease
SS7-1. The Use of High Dose Immunoablative Therapy with Hematopoietic Stem Cell Support Therapy in the Treatment of Severe Autoimmune Diseases
Tyndall Alan, Gratwohl Alois (Switzerland)
SS7-2. Autologous Stem Cell Transplants in Treatment of Multiple Sclerosis: Where We Stand and Future Prospects
Fassas Athanasios (Greece)
SS7-3. Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure?
Burt Richard K., Slavin Shimon, Burns William H., Marmont Alberto M. (Israel, Italy)
Contents
SS8. Recent Advances for Management of Hematologic Malignancies
SS8-1. Molecular Pathogenesis of AML (Mouse Models of Acute Myeloid Leukemia with AML1-ETO Fusion Proteins)
Zhang Dong-Er (USA)
SS8-2. A Novel Therapeutic Approach for Hematological Malignancies Based on Cellular Differentiation and Apoptosis
Kizaki Masahiro (Japan), Nakazato Tomonori (Japan), Ito Keisuke (Japan), Kawamura Chiharu (Japan), MiyakawaYoshitaka (Japan), Ikeda Yasuo (Japan)
SS8-3. Progress in the Treatment of Acute Myeloid Leukaemia in Adults
Newland Adrian (UK)
Contents
SS9. Molecular Pathogenesis of Hematologic Malignancies
SS9-1. The Stem Cell Leukaemia Gene: Establishing the Transcriptional Programme for Blood
Green A.R. (UK)
SS9-2. Apoptosis-Based Therapies for Neoplastic Diseases
Reed John C. (USA)
SS9-3. Cell Cycle Regulation: Mechanisms and Therapeutics
Reddy E. Premkumar (USA)
Contents
SS10. Gene Therapy and Manipulation of Hematopoietic Stem Cell
SS10-1. High Efficiency Gene Transfer to Human CD34+ Cells
Hong Youngtae (Korea), Lee Karim (Korea), Choi Ji Young (Korea), Yu Seung Shin (Korea), Kim Eunok (Korea), Sugimoto Y. (Japan), Ueno M. (Japan), Kato I. (Japan), Kim S. (Korea)
SS10-2. Development of Selective Amplifier Genes for Hematopoietic Stem Cell Gene Therapy
Ozawa Keiya (Japan), Hanazono Yutaka (Japan), Kume Akihiro (Japan), Nagashima Takeyuki (Japan), Ueda Yasuji (Japan), Terao Keiji (Japan), Hasegawa Mamoru (Japan)
SS10-3. Tumor Specific Targeting of Adenoviral Vectors to Cancer
Deisseroth A. (USA), Zhang L. (USA), Tang Y.C. (USA), Liu Y.Z. (USA), Maynard J. (USA), Chung I. (USA), Won J.H. (USA), Shin D.B. (USA), Akbulut H. (USA)
Contents
SS11. Immune and Cell Therapy for Hematological Disorders
SS11-1. Immune and Cell Therapy of Hematologic Malignancies
Kipps Thomas J. (USA)
SS11-2. Identification of Novel Minor Histocompatibility Antigens Responsible for Graft-versus-leukemia (GVL) Effect on Chronic Myeloid Leukemia: Usefulness of Determining The Clonotype of T Cells Associated with GVL Effect after Donor Leukocyte Infusion
Nakao Shinji (Japan)
SS11-4. Role of NKT Cells and ес-Galactosyl Ceramide
Shimosaka Akihiro (Japan)
Contents
SS12. Hematological Disorders in the Developing Countries
SS12-1. Restructuring of International Council for Standardization in Haematology (ICSH) in Asia
N Tatsumi (Japan), S.M. Lewis (U.K.)
SS12-2. Some Hematological Problems in Indonesia
Timan Ina S. (Indonesia), Aulia Diana (Indonesia), Atmakusuma Djumhana (Indonesia), Sudoyo Aru (Indonesia), Windiastuti Endang (Indonesia), Kosasih Agus (Indonesia)
SS12-3. New Strategies for the Diagnosis and Screening of Malaria
S.H. Lee, U.A.K.Kara, E.Koay, M.A.Lee, S.Lam, D.Teo (Singapore)
SS12-4. Laboratory Practice at the Periphery in Developing Countries
Lewis S.M. (UK)
Contents
SS13. Infections in Hematologic Malignancies
SS13-1. New Strategies in the Management of Herpesvirus Infections
Ljungman Per (Sweden)
SS13-2. New Strategy for Fungal Infections
Pauw Ben De (Netherlands)
Contents
SS14. Asian Cooperation in the Field of Hematology
SS14-1. Stem Cell Transplantation for Thalassemia
Issaragrisil Surapol (Thailand)
SS14-2. Current Status of Japan Marrow Donor Program (JMDP) and Its Roles in International Cooperation
Okamoto Shinichiro (Japan)
SS14-3. Marrow Donor Registry and Cord Blood Bank in Taiwan
Lee Tsung Dao (Taiwan)
SS14-4. Allogeneic Placental/Umbilical Cord Blood Transplantation and Its Impact on Regenerative Medicine
Asano Shigetaka (Japan)
SS14-5. Current Study of APL Treatment in China
Lu Dao-Pei (China), Qin Wang (China)
Contents
SS16. Lymphoma
SS16-1. Translational Development of Active Immunotherapy For Hematologic Malignancies
Kwak Larry W. (USA)
SS16-2. OX40/gp34 (OX40L) and Adult T-cell Leukemia (ATL)
Uchiyama Takashi (Japan)
SS16-3. Molecular Mechanisms of Lymphomagenesis through Transcriptional Disregulation by Chromosome Translocation
Seto Masao (Japan)
SS16-4. Immunoreceptor Complexes of the Innate Immune System
Kim Yoon Berm (USA), Yim Daesong (USA)
Contents
SS17. Multiple Myeloma
SS17-1. Growth Mechanism of Human Myeloma Cells by Interleukin-6
Kawano Michio M. (Japan), Ishikawa Hideaki (Japan), Tsuyama Naohiro (Japan), Abroun Saeid (Japan), Liu Shangqin (Japan), Li Fu-Jun (Japan), Otsuyama Ken-ichiro (Japan), Zheng Xu (Japan)
SS17-2. New Insights into Role of Microenvironment in Multiple Myeloma
Guido J. Tricot (USA)
SS17-3. Early Results of Total Therapy II in Multiple Myeloma: Implications of Cytogenetics and FISH
Barlogie Bart (USA), Shaughnessy John D. (USA)
SS17-4. Novel Biologically Based Therapies for Multiple Myeloma
Munshi Nikhil C. (USA), Hideshima Teru (USA), Chauhan Dharminder (USA), Richardson Paul (USA), Anderson Kenneth C. (USA)
Contents
SS18. Update on Hemostasis and Thrombosis
SS18-1. Thrombopoietin: From Theory to Reality
Kaushansky Kenneth (USA)
SS18-2. Heparin-induced Thrombocytopenia: Molecular Pathogenesis
Lee Seon Ho (Korea), Liu Chao Yan (USA), PaoloVisentin Gian (USA)
SS18-3. Structure and Function of Human Fibrinogen Inferred from Dysfibrinogens
Matsuda Michio (Japan), Sugo Teruko (Japan)
SS18-4. Neonatal Alloimmune Thrombocytonpenia Due to HLA Antibodies
Han Kyou-Sup (Korea), Song Eun-Young (Korea), Park Myoung-Hee (Korea)
Contents
SS19. Some Modifications in the Stem Cell Transplantation (SCT) Procedures Render Them Affordable for Developing Countries
SS19-1. The Importance of Lowering the Costs of Stem Cell Transplantation in Developing Countries
Barr Ronald D. (Canada)
SS19-2. Update on Non-Myeloablative Stem Cell Transplantation for Hematologic Malignancies
Giralt S. (USA)
SS19-3. Allogeneic Stem Cell Transplantation Using Non-Myeloablative Conditioning Regimens: Results of the Mexican Approach
Ruiz-Arguelles Guillermo J. (Mexico)
SS19-4. The Simplification of The SCT Procedures in Developing Countries has Resulted in Cost-Lowering and Availability to More Patients
Gomez-Almaguer David (Mexico)
Contents
PS. Current Status and Future Direction of International Registries
PS1. Goals and Activities of the WMDA
Gahrton Gosta (Sweden)
PS2. The Role of the EBMT Activity Survey in the Management of Hematopoietic Stem Cell Transplantation
Gratwohl Alois (Switzerland)
PS3. The International Bone Marrow Transplant Registry
Goldman John (USA), Horowitz Mary M. (USA)
Contents
GL. Special Guest Lecture
GL1. Molecular Nature of Antigens Implicated in Immune Neutropenias
Bux Juergen (Germany)
GL2. Molecular Mechanism of the LMP1-induced Downregulation of CD99 in Hodgkin and Reed-Sternberg Cells
Park Seong Hoe (Korea)
Contents